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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRF1
All Species:
16.67
Human Site:
S578
Identified Species:
28.21
UniProt:
Q92994
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92994
NP_001510.2
677
73840
S578
S
R
R
R
T
P
A
S
R
S
G
A
D
P
V
Chimpanzee
Pan troglodytes
XP_510208
819
88957
S720
S
R
R
R
T
P
A
S
R
S
G
A
D
P
V
Rhesus Macaque
Macaca mulatta
XP_001098066
599
65136
V507
S
R
S
G
A
D
P
V
T
S
V
G
K
R
L
Dog
Lupus familis
XP_548005
637
70371
P545
A
S
R
S
G
A
D
P
V
T
S
V
G
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFK2
676
73781
T577
S
R
R
K
R
A
T
T
R
N
S
A
D
P
G
Rat
Rattus norvegicus
NP_001100231
686
74096
T587
S
R
R
K
R
A
A
T
R
N
S
A
D
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421405
681
75256
S583
S
R
R
K
S
I
A
S
R
N
I
A
S
P
V
Frog
Xenopus laevis
NP_001088063
660
73751
R565
N
S
N
Q
L
S
R
R
K
S
A
A
S
R
S
Zebra Danio
Brachydanio rerio
NP_956183
693
76806
Q584
R
L
T
R
R
K
K
Q
P
N
K
S
N
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650616
662
73627
A570
I
V
E
E
G
P
V
A
S
K
S
R
G
N
R
Honey Bee
Apis mellifera
XP_623775
648
73504
K556
N
N
I
A
S
S
N
K
P
I
T
S
I
T
K
Nematode Worm
Caenorhab. elegans
NP_495526
759
84015
S614
N
L
K
V
E
S
A
S
P
S
T
S
E
V
S
Sea Urchin
Strong. purpuratus
XP_794011
768
83924
G647
S
T
P
F
R
A
G
G
V
S
Q
G
A
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29056
596
66888
K504
E
Q
E
S
K
R
L
K
Q
E
A
D
I
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
86.4
82.7
N.A.
89.8
81.6
N.A.
N.A.
78.1
72.5
65.9
N.A.
42.5
43.4
32.4
46.3
Protein Similarity:
100
80
87
85.9
N.A.
93.3
86
N.A.
N.A.
87
84.7
77.6
N.A.
59.6
61.7
50
60.1
P-Site Identity:
100
100
20
6.6
N.A.
46.6
53.3
N.A.
N.A.
60
13.3
6.6
N.A.
6.6
0
20
13.3
P-Site Similarity:
100
100
26.6
20
N.A.
66.6
73.3
N.A.
N.A.
80
33.3
26.6
N.A.
13.3
20
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
29
36
8
0
0
15
43
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
0
0
0
0
8
29
0
0
% D
% Glu:
8
0
15
8
8
0
0
0
0
8
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
15
0
8
8
0
0
15
15
15
0
22
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
8
0
0
0
8
8
0
15
0
0
% I
% Lys:
0
0
8
22
8
8
8
15
8
8
8
0
8
8
8
% K
% Leu:
0
15
0
0
8
0
8
0
0
0
0
0
0
8
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
22
8
8
0
0
0
8
0
0
29
0
0
8
8
0
% N
% Pro:
0
0
8
0
0
22
8
8
22
0
0
0
0
36
0
% P
% Gln:
0
8
0
8
0
0
0
8
8
0
8
0
0
8
0
% Q
% Arg:
8
43
43
22
29
8
8
8
36
0
0
8
0
15
15
% R
% Ser:
50
15
8
15
15
22
0
29
8
43
29
22
15
0
15
% S
% Thr:
0
8
8
0
15
0
8
15
8
8
15
0
0
8
8
% T
% Val:
0
8
0
8
0
0
8
8
15
0
8
8
0
8
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _